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Forschung
Organisation
Production of recombinante laccase
01.02.2006 - 30.06.2007
Research funding project
This project aims at the heterologeous expression of the Melanocarpus albomyces laccase gene in Trichoderma reesei in fed-batch culture with special emphasis on the volumetric productivity of the cultivation. Different feeding strategies will be applied in order to maximize the space-time-yield of recombinant enzyme formation. As the promotor used in the recombinant strain is obtained from a cellulase gene of Trichoderma, the hypothesis to be prooven is, that protein expression will be high under conditions of low specific growth rates.
People
Project leader
Bernhard Adamitsch
(E166)
Institute
E166 - Institute of Chemical, Environmental and Bioscience Engineering
Grant funds
Hochschuljubiläumsfonds der Stadt Wien (National)
Anniversary Fund for Higher Education of the City of Vienna
Keywords
German
English
Zulaufverfahren
Fed-batch culture
Laccase
Laccase
Melanocarpus
Melanocarpus
Publications
Publications