Evaluation of Teriparatide Effects on Bone Strength Assessed by High-Resolution Computed Tomography Based Finite-Element-Analysis

01.12.2005 - 30.09.2008
Assigned research project
The limitations of DXA in assessing treatment effects in osteoporosis are well established. Bone strength is affected not only by bone mass but also by bone quality. For vertebral bone strength the integrity of the internal trabecular network represents one key factor of bone quality. We propose to develop finite element (FE) models based on high resolution computed tomography data to assess bone strength in vivo.

People

Project leader

Project personnel

Institute

Contract/collaboration

  • Lilly Deutschland GmbH

Research focus

  • Computational System Design: 50%
  • Modeling and Simulation: 50%

Keywords

GermanEnglish
ComputertomografieComputed Tomography
Finite Elemente AnalyseFinite Element Analysis
KnochenfestigkeitBone Strength
TeriparatidTeriparatide

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