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Toxico-genomics of Fusarium mycotoxin action in plant and human health: new approaches for safer foods
01.01.2003 - 31.05.2006
Forschungsförderungsprojekt
The main goals of this interdisciplinary project is to use the tools of functional genomics to obtain insights into the mechanisms of pathogenicity of the fungus Fusarium graminearum , which produces mycotoxins contaminating agricultural products, and into the mechanisms of Fusarium resistance in wheat, maize and the model plant Arabidopsis thaliana . The secondary metabolome of the fungus will be characterized and the role of particular compounds in virulence will be investigated. The toxicological effects of Fusarium metabolites and detoxification reactions in human and plant cells will be studied. The knowledge obtained will be applicable for development of new control strategies for Fusarium , and especially for breeding important crop plants with increased resistance, which prevent the accumulation of Fusarium mycotoxins in food and animal feed.
Personen
Projektleiter_in
Robert Mach
(E166)
Projektmitarbeiter_innen
Kurt Brunner
(E166)
Georg Reischer
(E166)
Institut
E166 - Institute of Chemical, Environmental and Bioscience Engineering
Grant funds
BM für Wissenschaft, Forschung und Wirtschaft (bm:wfw) (National)
Federal Ministry of Science and Research (bm:wf)
Schlagwörter
Deutsch
Englisch
Fusarium graminearum
Fusarium graminearum
Mykotoxine
Mycotoxins
Ährenfusariose
Fusarium head blight
Zeralenon
zeralenon
Externe Partner_innen
Seibersdorf Labor GmbH
Universität für Bodenkultur
Munich Information Center for Protein Sequences
Publikationen
Publikationsliste