The focus of this joint action, EU-WISH, is to support activities to enhance, extend and consolidate wastewater surveillance for public health. EU-WISH will improve national public health wastewater surveillance capacities by strengthening knowledge exchange and sharing best practices based on scientific evidence. The activities of this joint action will target and bring together relevant structures at national level and will facilitate the integration and complementarity of wastewater surveillance with other surveillance systems with a public health perspective to strengthen preparedness and response to cross border health threats. EU-WISH will help align epidemiological and technical methods for a range of targets for wastewater surveillance. EU-WISH supports the policy priority to strengthen the capability of the European Union for prevention of, preparedness for, and rapid response to, serious cross-border threats to health particularly through supporting data gathering, information exchange and surveillance. EU-WISH contributes to the achievement of the EU4Health Programme’s general objective of protecting people in the Union from serious cross-border threats to health and strengthening the responsiveness of health systems and coordination among the Member States. EU-WISH is a strong consortium that can contribute to a vision and activities for wastewater surveillance at not only European, but also global level.