Migration of contaminants out of plastic packaging materials (also described as food contact materials) into food has already been a research topic for many years. Meanwhile legal regulations were set up with a positive list including migration limits of substances to be used in plastic materials that are designed to come in contact with food. There are quite a number of more or less toxic substances used as additives (like plasticizers, stabilizers, antioxidants, residues of solvents, monomers and others) in the process of making plastics. As it is not desirable to get these compounds into food, many methods have been developed to analyze and quantify migrating compounds. However, food differs in many properties, so food simulants have been defined that shall cover all different foods in order to make standardized analysis possible. It was the goal of the EU project QLK1-CT2002-2390 "Foodmigrosure" to create a mathematically based modelling programme to give industry, public authorities and consumer organisations a means of risk assessment. In this project many analyses were carried out to generate a data pool which is the basis of the work. However, some of the analysed compounds migrated in a not expected way concerning the chemical properties of the foods surveyed. Considerations have been set on possible reasons for these results and lead to the assumption that the structure of food has a great impact on migration as well. Further literature supports this assumption. Some work has already been done in the field of electron microscopy to visualize (micro) structure of food. Also process parameters have an impact on food structure of foods (for example: process cheese, chocolate). It seems that the mechanisms of the phenomenon of migration are not entirely understood at all. In order to find explanations for not expected results from the EU project "Foodmigrosure" we shall try to find correlations between food structure elements and migration rates. This will be done by analysis of structure (microscopic, spectroscopic) and analysis of migration rates (using already certified methods). The ambition is to gain knowledge on the specific systems of food and plastic packaging materials