A 3D finite element model of damage and augmentation of the human vertebral body

31.12.2004 - 31.03.2006
Forschungsförderungsprojekt
Percutaneous vertebroplasty (PV) is an effective treatment option for osteoporotic vertebral fractures. Until now, polymethylmetacrylate (PMMA) remains the most common biomaterial used for PV, but has some specific disadvantages like its high polymerization temperature, neurotoxicity and its high stiffness which leads to an increased fracture rate of adjacent vertebral bodies. Furthermore, there are major complications in PV associated with biomaterial leakage and extravasation that are correlated with the injected volume and inversely correlated with the viscosity of the biomaterial. The goal of the project is to develop an experimentally validated finite element model of the human vertebra to determine the suitable mechanical characteristics of a novel biomaterial for PV.

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Schlagwörter

DeutschEnglisch
AugmentationAugmentation
Biomaterialbiomaterial
Frakturfracture
OsteoporoseOsteoporosis
Perkutane Vertebroplastiepercutaneous vertebroplasty
Wirbelkörpervertebral bone

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