Co-creative Cohabitation Network (CoCoNet) proposes a novel approach to inner-city development that fosters multi-functionality mindsets to achieve less car-dependency towards a spatially just, resilient and livable city. The unique approach of CoCoNet is to provide a methodology to highlight spatial potentials and to restructure and redistribute streetscape, using integrated modeling revealingsynergies between sustainable mobility, noise dissemination, climate adaptation and biodiversity. Although digital models of theindividual aspects are available, such an integrating, model-supported planning approach is currently missing in practice, but urgently needed to develop smart and sustainable urban neighborhoods of the future.  CoCoNet focuses on urban structure at the district level and concentrates on combining mobility measures with nature-based solutions. It merges two integrated co-creative processes of (1)modeling and (2) planning and design, involving the city administration, local initiatives and urban design students. CoCoNet will go beyond current urban sustainability approaches by providing a planning methodology that can be directly applied in the creation of vibrant, sustainable urban neighborhoods giving valuable support to policy and decision makers. The project will also go beyond existing urban biodiversity studies by making socio-ecological aspects and the cohabitation between humans and other organisms a central point in the urban planning process.