164.356 Metabolomics
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2020W, VO, 1.3h, 2.0EC


  • Semester hours: 1.3
  • Credits: 2.0
  • Type: VO Lecture
  • Format: Online

Learning outcomes

After successful completion of the course, students are able to identify metabolomic questions in basic and applied research and quality control. The learning goal is to know different metabolomic strategies and choose the appropriate strategy for diverse questions. Students will be able to design different metabolomic experiments and theoretically apply sample preparation and analyses and bioinformatic analyses. This includes knowledge of metabolite extraction from biological matrices, separation techniques, such aschromatography (LC, GC, TLC), (tandem) mass spectrometry (MS/MS), ion mobility (IMS) and LC-(IMS)-MS/MS of for identification, characterisation and quantification and functional annotation of metabolites. Moreover, students will learn to apply statistical tools to metabolomic data to calculate significant quantitative changes.

Subject of course

Metabolomic strategies and methods: definition of research question, different sample preparation methods, identification, quantitation and annotation of metabolites, structural characterisation of metabolites,high-through-put technologies, (tandem) mass spectrometry, ion mobility, liquid/gas chromatography, bioinformatic tools

Teaching methods

Lecture with practical exercises (e.g. manual MS/MS spectrum interpretation, usage of webtools)

presentation and discussion of examples of metaboomic applications

Mode of examination




Course dates

Tue16:00 - 19:0013.10.2020 - 17.11.2020 (LIVE)GoToMeeting
Metabolomics - Single appointments
Tue13.10.202016:00 - 19:00 GoToMeeting
Tue20.10.202016:00 - 19:00 GoToMeeting
Tue27.10.202016:00 - 19:00 GoToMeeting
Tue03.11.202016:00 - 19:00 GoToMeeting
Tue10.11.202016:00 - 19:00 GoToMeeting
Tue17.11.202016:00 - 19:00 GoToMeeting

Examination modalities

Presentation and discussion of a metabolomics application example

Course registration

Begin End Deregistration end
06.10.2020 09:00 31.10.2020 18:00


Study CodeObligationSemesterPrecon.Info
066 490 Technical Chemistry Mandatory elective


Copies of the ppt-slides will be available via Tuwel/TISS.

Previous knowledge

Knowledge of biochemistry and instrumental analytical chemistry is essential. Instrumental bioanalytics is recommended.