322.071 Transport Phenomena in Biological Systems
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2018W, VO, 2.0h, 3.0EC

Properties

  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture

Aim of course

Understanding the dynamics of physical, chemical and biological processes that control heat, mass and momentum transport in an organism is extremely important in physiology and bioengineering. Since transport phenomena influence both normal and pathological functions of cells and organisms, their knowledge is also fundamental to design medical devices: dialysis machines, accretion of artificial organs on scaffolds and intravenous feeding among others. In this course, the physics of biological flows for medical applications is explored. Particular attention is paid both to develop physical intuition, and to use appropriate mathematical modelling skills. The course will cover basic concepts of fluid mechanics, transport of heat, mass and momentum and biochemical interactions. [Examples and problems discussed during lectures will be solved analytically and/or numerically, see Ubung].

Subject of course

  1. Introduction: The role of transport processes in biological systems; Conservation equations; dimensional analysis and scales of motions; Transport by diffusion; Transport by convection;

  2. Fluid Flow in the Circulation and Tissues: Oscillating flow in a cylindrical tube; Flow in Curved Vessels; Flow in Branching Vessels; Flow in arteries (Carotid Artery, Aorta, Coronary Arteries); Wall elasticity; Arterial Fluid Dynamics and Atherosclerosis; Heart-Valve Hemodynamics;

  3. Mass Transport in Biological systems - Diffusion: Fick's law; Diffusion through a film; Diffusion through porous media and through porous membranes; Diffusion with reactions;

  4. Mass Transport in Biological systems - Convection: Convective transport; Transport from an oxygen bubble; Convective transport with reaction;

Additional information

Exams:
3 VO exam dates each semester. Each VO exam covers the entire program of the VO lectures.

Structure of the exam:
-) Each exam consists of 2/3 problems
-) Each problem is divided into parts (2 or 3, typically).
A score is associated to each part (the maximum cumulative score considered to calculate the final grade is 100).
You should solve each problem by applying the correct equations and by providing the required results.

 

Scores:
Your grade will be assigned as follows:
SCORE                GRADE
<50   -> (fail)          5
51-65 -> (pass)      4
66-73 -> (pass)      3
74-85 -> (pass)      2
>86 -> (pass)         1

NOTE: Depending on the overall behavior of the class, the score ranges given above might change and shift towards lower values.
For instance, if scores are all below 85  then  ranges could be as follows:
SCORE                GRADE
<45   -> (fail)          5
46-60 -> (pass)      4
61-68 -> (pass)      3
69-80 -> (pass)      2
>81 -> (pass)         1

Lecturers

Institute

Course dates

DayTimeDateLocationDescription
Wed10:00 - 12:0003.10.2018 - 16.01.2019HS 11 Paul Ludwik Transport phenomena in biological systems
Mon13:30 - 15:0026.11.2018HS 11 Paul Ludwik Transport phenomena in biological systems
Transport Phenomena in Biological Systems - Single appointments
DayDateTimeLocationDescription
Wed03.10.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed10.10.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed17.10.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed24.10.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed31.10.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed07.11.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed14.11.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed21.11.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Mon26.11.201813:30 - 15:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed28.11.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed05.12.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed12.12.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed19.12.201810:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed09.01.201910:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems
Wed16.01.201910:00 - 12:00HS 11 Paul Ludwik Transport phenomena in biological systems

Exams

DayTimeDateRoomMode of examinationApplication timeApplication modeExam
Fri13:00 - 15:0029.01.2021GM 4 Knoller Hörsaal - TCH written01.01.2021 08:00 - 22.01.2021 18:00TISSExam-VO
Fri18:00 - 19:3005.03.2021Seminarraum BA 08A written19.02.2021 12:00 - 26.02.2021 12:00TISSExam-VO
Tue - 04.05.2021written12.04.2021 12:00 - 30.04.2021 12:00TISSExam-VO
Wed - 16.06.2021written14.05.2021 12:00 - 07.06.2021 12:00TISSExam-VO

Course registration

Not necessary

Curricula

Study CodeSemesterPrecon.Info
066 453 Biomedical Engineering

Literature

No lecture notes are available.

Previous knowledge

Suggested readings:

  • R. B. Bird, W. E. Stewart, E. N. Lightfoot, Transport Phenomena, Ed. John Wiley and Sons, 1960
  • G. A. Truskey, F. Yuan, D. F. Katz, Transport phenomena in biological systems, Ed. Prentice-Hall, 2010

Language

English