317.532 Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2024S, VO, 2.0h, 3.0EC

Properties

  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture
  • Format: Presence

Learning outcomes

After successful completion of the course, students are able to describe and explain experimental methods for structural and mechanical characterization of biological tisses. Students will further be able to describe and explain the most important state-of-the-art instruments used for such characterization as well as details on sample preparation, data analysis and potential sources for errors and/or artefacts.

Subject of course

The following techniques will be explained in terms of measurement principles and common data analysis procedures:

  • Introduction and Macromechanical tests
  • Micro- and Nanoindentation (conventional and AFM-based), Reference point microindentation, techniques, instrumentation, measurements, contact mechanics and resulting analysis techniques, pitfalls and problems
  • Atomic force microscopy (AFM) imaging modes, force mode (indentation, force spectroscopy mode) and combination with mechanical testing and sample preparation considerations for AFM experiments
  • Scanning electron microscopy, review of measurement principle, secondary electron imaging mode, backscattered imaging mode and quantitative backscattered imaging mode
  • Focused Ion Beam milling of hard tissue structures and theory, current research, limitations and challenges
  • Miniature and micro-mechanical tests of biological tissues
  • Micro-computed tomography, morphological parameters, porosity, crack propagation
  • Small angle x-ray scattering, principles, measurement of bone hydroxyapatite crystal T-parameter, collagen banding and collagen strain measurement during tensile loading
  • Raman-spectroscopy & FTIR, measurement principles and application to bone
  • Polarized light microscopy, Second harmonic generation, Quantitative polarized light microscopy and collagen orientation

Teaching methods

Lecture supported by digital presentations; discussion of case studies

Mode of examination

Oral

Lecturers

Institute

Course dates

DayTimeDateLocationDescription
Fri09:00 - 11:0001.03.2024 - 03.05.2024Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu09:00 - 11:0007.03.2024 - 16.05.2024Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues - Single appointments
DayDateTimeLocationDescription
Fri01.03.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu07.03.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri08.03.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu14.03.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri15.03.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu21.03.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri22.03.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu11.04.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri12.04.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu18.04.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri19.04.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu25.04.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri26.04.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu02.05.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues
Fri03.05.202409:00 - 11:00Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Thu16.05.202409:00 - 11:00Seminarraum BE 01 Experimental Mechanics and Characterisation of Biological Tissues

Examination modalities

Oral exam at the end of the term or further along the line on appointment. Estimated duration: … minutes

Exams

DayTimeDateRoomMode of examinationApplication timeApplication modeExam
Wed09:00 - 12:0019.06.2024Seminarraum BE 01 oral05.06.2024 17:00 - 14.06.2024 22:00TISSExam EMCT

Course registration

Begin End Deregistration end
01.02.2024 09:00 29.03.2024 22:00 29.03.2024 22:00

Curricula

Study CodeObligationSemesterPrecon.Info
066 453 Biomedical Engineering Not specified

Literature

No lecture notes are available.

Language

English