317.532 Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2020S, VO, 2.0h, 3.0EC

Properties

  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture

Learning outcomes

After successful completion of the course, students are able to describe and explain experimental methods for structural and mechanical characterization of biological tisses. Students will further be able to describe and explain the most important state-of-the-art instruments used for such characterization as well as details on sample preparation, data analysis and potential sources for errors and/or artefacts.

Subject of course

The following techniques will be explained in terms of measurement principles and common data analysis procedures:

  • Introduction and Macromechanical tests
  • Micro- and Nanoindentation (conventional and AFM-based), Reference point microindentation, techniques, instrumentation, measurements, contact mechanics and resulting analysis techniques, pitfalls and problems
  • Atomic force microscopy (AFM) imaging modes, force mode (indentation, force spectroscopy mode) and combination with mechanical testing and sample preparation considerations for AFM experiments
  • Scanning electron microscopy, review of measurement principle, secondary electron imaging mode, backscattered imaging mode and quantitative backscattered imaging mode
  • Focused Ion Beam milling of hard tissue structures and theory, current research, limitations and challenges
  • Miniature and micro-mechanical tests of biological tissues
  • Micro-computed tomography, morphological parameters, porosity, crack propagation
  • Small angle x-ray scattering, principles, measurement of bone hydroxyapatite crystal T-parameter, collagen banding and collagen strain measurement during tensile loading
  • Raman-spectroscopy & FTIR, measurement principles and application to bone
  • Polarized light microscopy, Second harmonic generation, Quantitative polarized light microscopy and collagen orientation

Teaching methods

Lecture supported by digital presentations; discussion of case studies

Mode of examination

Oral

Lecturers

Institute

Course dates

DayTimeDateLocationDescription
Thu09:00 - 10:3005.03.2020 - 12.03.2020Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Fri09:00 - 10:3006.03.2020 - 13.03.2020Seminarraum BE 01 Lecture
Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues - Single appointments
DayDateTimeLocationDescription
Thu05.03.202009:00 - 10:30Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Fri06.03.202009:00 - 10:30Seminarraum BE 01 Lecture
Thu12.03.202009:00 - 10:30Seminarraum BE 01 VO Experimental Mechanics and Characterisation of Biological TissuesTissue Biomechanics
Fri13.03.202009:00 - 10:30Seminarraum BE 01 Lecture

Examination modalities

Oral exam at the end of the term or further along the line on appointment. Estimated duration: … minutes

Course registration

Begin End Deregistration end
30.01.2020 09:00 27.03.2020 22:00 27.03.2020 22:00

Curricula

Study CodeSemesterPrecon.Info
066 453 Biomedical Engineering

Literature

No lecture notes are available.

Language

English