317.532 Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2018S, VO, 2.0h, 3.0EC
Quinn ECTS survey


  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture

Aim of course

Introduction to the experimental techniques available for evaluation of the hierarchical structure and mechanical properties of bone and soft biological tissues from the macro- to the nanoscale

Subject of course

The following techniques will be explained in terms of measurement principles and common data analysis procedures:

  • Introduction and Macromechanical tests
  • Micro- and Nanoindentation (conventional and AFM-based), Reference point microindentation, techniques, instrumentation, measurements, contact mechanics and resulting analysis techniques, pitfalls and problems
  • Atomic force microscopy (AFM) imaging modes, force mode (indentation, force spectroscopy mode) and combination with mechanical testing and sample preparation considerations for AFM experiments
  • Scanning electron microscopy, review of measurement principle, secondary electron imaging mode, backscattered imaging mode and quantitative backscattered imaging mode
  • Focused Ion Beam milling of hard tissue structures and theory, current research, limitations and challenges
  • Miniature and micro-mechanical tests of biological tissues
  • Ultrasound & Scanning Acoustic Microscopy
  • Micro-computed tomography, morphological parameters, porosity, crack propagation
  • Small angle x-ray scattering, principles, measurement of bone hydroxyapatite crystal T-  parameter, collagen banding and collagen strain measurement during tensile loading
  • Raman-spectroscopy & FTIR, measurement principles and application to bone
  • Polarized light microscopy, Second harmonic generation, Quantitative polarized light microscopy and collagen orientation



Course dates

Thu09:00 - 10:3008.03.2018 - 28.06.2018Seminarraum BE 01 Lecture
Experimental Mechanics and Characterization of the Hierarchical Structure of Biological Tissues - Single appointments
Thu08.03.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu15.03.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu22.03.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu12.04.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu19.04.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu26.04.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu03.05.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu17.05.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu24.05.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu07.06.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu14.06.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu21.06.201809:00 - 10:30Seminarraum BE 01 Lecture
Thu28.06.201809:00 - 10:30Seminarraum BE 01 Lecture


DayTimeDateRoomMode of examinationApplication timeApplication modeExam
Wed09:00 - 12:0014.06.2023Seminarraum BE 01 oral31.05.2023 17:00 - 09.06.2023 22:00TISSExam EMCT

Course registration

Begin End Deregistration end
01.02.2018 09:00 30.03.2018 23:00 30.03.2018 23:00


Study CodeObligationSemesterPrecon.Info
066 453 Biomedical Engineering Not specified


No lecture notes are available.