172.695 Biochemistry I (Fundamentals)
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2019W, VO, 2.0h, 3.0EC

Properties

  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture

Learning outcomes

After successful completion of the course, students are able to describe the structure and function of the most important groups of biomolecules (proteins, nucleic acids, carbohydrates and lipids). Furthermore, they are able to explain essential molecular biological mechanisms of the cell, the biosynthesis of DNA, RNA & proteins. Using selected examples, students can demonstrate the regulation of metabolism in the cell as well as signal transduction. They will be able to describe the function, nomenclature and properties of enzymes and to describe in detail important anabolic and catabolic metabolic pathways and their regulation (including glycolysis, citrate cycle, respiratory chain, photosynthesis, fatty acid biosynthesis and nitrogen cycle).

Subject of course

1 1. Basics of Biochemistry

2. Biomolecules

  • Proteins
  • Nucleic acids
  • Carbohydrates and lipids

3. Molecular biology

  • Biosynthesis of DNA and RNA (replication, transcription)
  • Protein Biosynthesis (Translation)
  • Metabolic Regulation & Signal Transduction

4. Metabolism

  • General principles
  • Biothermodynamics
  • Enzyme und Enzymkinetik

4.1 Catabolism 

  • Carbohydrate degradation (glycolysis, NADH regeneration, pentose phosphate pathway, pyruvate degradation, respiratory chain, citric acid cycle ...)
  • Fat loss (lipases, glycerol degradation, ß-oxidation)
  • Protein degradation (proteases, amino acid degradation, urea cycle)

4.2 Anabolism

  • Photosynthesis: dark reaction and light reaction
  • Gluconeogenesis
  • Glycogen metabolism
  • Fatty acid biosynthesis
  • shuttle systems
  • Nitrogen fixation and nitrogen circulation

Teaching methods

Lecture with Power point presentation

Mode of examination

Written

Lecturers

Institute

Course dates

DayTimeDateLocationDescription
Fri10:00 - 12:0029.11.2019 - 31.01.2020GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed10:00 - 12:0004.12.2019 - 29.01.2020GM 5 Praktikum HS- TCH Biochemie I
Biochemistry I (Fundamentals) - Single appointments
DayDateTimeLocationDescription
Fri29.11.201910:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed04.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Basics in biochemistry
Fri06.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed11.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri13.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed18.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri20.12.201910:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed08.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri10.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed15.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri17.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed22.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri24.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry
Wed29.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Grundlagen der Biochemie
Fri31.01.202010:00 - 12:00GM 5 Praktikum HS- TCH Basics in Biochemistry

Examination modalities

A written examination on the lecture contents. The exam lasts 120 minutes and consists of 10 tasks. These tasks are composed of: 

  • 10 questions per topic/topic area/randomly distributed over the topics Fundamentals of Biochemistry, Biomolecules, Molecular Biology, Metabolism (Anabolism & Catabolism)

A total of 100 points are awarded for the examination; 100-88 points correspond to "Very Good", 87-75 points to "Good", 74-62 points to "Satisfactory", 61-50 points to "Satisfactory" and less than 50 points to "Unsatisfactory", which means that the examination must be repeated. 

Permitted aids in the examination are: none

Exams

DayTimeDateRoomMode of examinationApplication timeApplication modeExam
Fri14:00 - 16:0003.05.2024GM 2 Radinger Hörsaal - TCH written03.04.2024 12:00 - 01.05.2024 12:00TISSBiochemie I Prüfung SS24_2
Fri14:00 - 16:0007.06.2024GM 2 Radinger Hörsaal - TCH written07.05.2024 12:00 - 05.06.2024 12:00TISSBiochemie I Prüfung SS24_3
Fri14:00 - 16:0005.07.2024GM 4 Knoller Hörsaal - VT written05.06.2024 12:00 - 03.07.2024 12:00TISSBiochemie I Prüfung SS24_5
Fri14:00 - 16:0030.08.2024GM 2 Radinger Hörsaal - TCH written30.07.2024 12:00 - 28.08.2024 12:00TISSBiochemie I Prüfung SS24_4

Course registration

Not necessary

Curricula

Study CodeObligationSemesterPrecon.Info
033 290 Technical Chemistry Mandatory3. Semester
066 473 Chemical and Process Engineering Mandatory elective
423 Subject: Chemistry Mandatory
735 Chemical Engineering Mandatory7. Semester

Literature

The power-point presentations of the lecture can be downloaded  from TISS. Literature recommendations are included. ATTENTION: they are not a script of the lecture, they merely serve the purpose to relief the student from drawing the shown slides. It is recommended to make records of the lecturers explanations.

Previous knowledge

Basic knowledge in chemistry, particularly on organic chemistry (natural components)

Language

German