Information on important processes with living cells, products, unit operations and integrated processes.
Scope, history and economics Biological materials - Microorganisms: Bacteria, yeasts, fungi (isolation), growth (kinetics, nutrients, metabolism), strain improvement (mutation, recomb. DNA, cell fusion) Process engineering: [cultivation media, sterilisation, oxygen supply, reactors, cultivation principles and parameters; down stream processes] Microbial biomass - baker's yeast, starter cultures/biol.insecticides Type 1 fermentations: Products from microbial cells: PHB, SCP; Enzyme Technology, immobilisation (racemic separation), Biocatalysis/Biotransformation, steroid transformation); anaerobic fermentations - Ethanol, lactic acid Type 2 Fermentations: Citric acid, amino acids; vinegar, gluconic acid Type 3 Fermentations: Secondary metabolites (antibiotics) Environmental Biotechnology Recombinant protein production (therapeutic proteins, vaccines, antibodies), Biotechnology of plant and animal cells Stoichiometrie and reaction kinetics Downstream Processing: Separation, Chromatographie Scale Up andintegrated processes SIP, CIP and pharmaceutical requirements
Oral exam. The bioengineering part will be examined by Prof. Christoph Herwig and the biotechnology part by Priv. Doz. Bernhard Seiboth. Registration via TISS. Meeting point for the exam is in the 3rd floor of the BH building.
Notice of removal have to be performed via TISS in time.
•Taschenatlas der Biotechnologie und Gentechnik Wiley-VCH
•Biotechnologie: eine Einführung mit Modellversuchen Enke Verlag Stuttgart
•Basic Biotechnology, 2nd ed. Cambridge University Press
•Biotechnologie für Einsteiger, Spektrum, 2006
•Bioprozesstechnik (H.Chmiel;Hrsg.), Spektrum, 2006
•Bioverfahrensentwicklung (W. Storhas); Wiley-VCH, Weinheim, 2003
•Bioreaction Engineering Principles (J.Nielsen, J.Villadsen); Plenum Press, London 2002
•Bioprocess Engineering Principles (Pauline M. Doran), 2012
