166.186 Applied Chemistry in medical research

2020S, SE, 2.0h, 2.0EC
TUWEL

Properties

  • Semester hours: 2.0
  • Credits: 2.0
  • Type: SE Seminar

Learning outcomes

After successful completion of the course, students are able to...

Learning/application of natural sciences principles onto scientific problems of medicine. Preparing of study designs, basic statistic considerations, CRFs, ethical proposals, etc. Training of laboratory specific approaches for the implementation of chemical-analytical basics for the elaboration of samples underlying complex protein matrix. Features to be emphasized: genomic and proteomic problems of infectiology, general immunology, hematology, embryology and iatrogenic apoptosis

Subject of course

Chemical techniques and analytical principles have to undergo a specific transformation (metaplasia) in order to become useful for the application on medical questions. Mandatory sequences and aims will be the items: genomics and proteomics of the human immune system. See below the main points of teaching shorthand: Adaptation of chemical methods and instruments to the medical needs, e.g. for the analysis of body fluids, human tissues and cultured cells; Evaluation of reference ranges plus interpretation; chemical subgrouping according to clinical points of view: diagnostics of enzymes and metabolic conditions, carbohydrate analytics, lipids, mineral/bone & iron metabolism, electrolytes, acid-base conditions and functional diagnostics, trace element & metal analyses (toxicology), hematology (incl. cytologigal diagnostics), etc. Main goal is the preparation of scientists for a professional handling of biochemical/biological/medical subjects, incl. protein analytics (proteomics)and detection of low concentrated biological antigens (PCR) in blood and human tissues. Analytics of gen expression in combination with proteomic analyis shall lead to relevant functional proteoms of high and low abundant (serum) proteins, thus resulting in the evaluation of biomarkers.

Teaching methods

Adaptation of chemical methods and instruments to the medical needs, e.g. for the analysis of body fluids, human tissues and cultured cells; Evaluation of reference ranges plus interpretation; chemical subgrouping according to clinical points of view: diagnostics of enzymes and metabolic conditions, carbohydrate analytics, lipids, mineral/bone & iron metabolism, electrolytes, acid-base conditions and functional diagnostics, trace element & metal analyses (toxicology), hematology (incl. cytologigal diagnostics), etc. Main goal is the preparation of scientists for a professional handling of biochemical/biological/medical subjects, incl. protein analytics (proteomics)and detection of low concentrated biological antigens (PCR) in blood and human tissues.

Mode of examination

Oral

Additional information

Please consider the plagiarism guidelines of TU Wien when writing your seminar paper: Directive concerning the handling of plagiarism (PDF)

Lecturers

Institute

Examination modalities

Oral exam

Course registration

Not necessary

Curricula

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Literature

No lecture notes are available.

Language

German