After successful completion of the course, students are able to explain the function of the most important ionization methods and mass analyzers as well as typical application examples in the field of biomedical and biotechnological research and engineering.

• Desorption/Ionization techniques for biomolecules: MALDI, ESI
  
• High resolution mass spectrometric analyzers: TOF, Orbitrap and FT-ion cyclotron resonance analyzer
• Fragmentation techniques
  
• Protein complexes, proteins, peptides, PTMs
• Lipids

• lecture
• Slides suitable to achieve the learning objective
• discussion of primary literature
  

The lecture will only be held if at least 3 students are present.

• oral examination as part of lecture (presentation and discussion of a key publication in biological mass spectrometry)

Copies of PPT slides will be available via Tuwel/TISS.

Basic knowledge of biochemistry and instrumental analytical chemistry beneficial