164.306 Organic Mass Spectrometry
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2022W, VO, 1.5h, 2.0EC


  • Semester hours: 1.5
  • Credits: 2.0
  • Type: VO Lecture
  • Format: Online

Learning outcomes

After successful completion of the course, students are able to explain the most important ionization techniques (EI, CI, ESI, MALDI, APCI, APPI) and mass analyzers (quadrupole, triple quadrupole, ion trap, time-of-flight analyzer, ion cyclotron, ion mobility) and name typical areas of application. This includes knowledge of MS / MS methods, the combination of ionization methods with suitable mass analyzers, knowledge about hybrid instruments and potential hyphenation with different separation methods (LC, GC). The students will also be able to interpret mass spectra, with a focus on fragmentation for molecules up to about 2000 Da.

Subject of course

Building on the knowledge from the basic courses, the following content is taught:

  • Principles and Mechanisms of hard and soft ionization techniques
  • Principles and capabilities of mass analyzers (low / high resolution mass analyzers)
  • Tandem and multistage mass spectrometer
  • Application of the methods to questions in the field of organic mass spectrometry (for example, polymers, natural products, medicines, etc.)

Teaching methods

  •  lecture - self study, presentation, discussion
  • Slides suitable to achieve the learning objective
  • Lecture slides with voice over if necessary 
  • Question and answer hours
  • exemplary videos
  • Learning of spectra interpretation using real examples

Mode of examination




Course dates

Thu17:00 - 19:0020.10.2022 - 26.01.2023Seminarraum BA 02C Vortragseinheiten
Organic Mass Spectrometry - Single appointments
Thu20.10.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten - erste Einheit am 27.10. (siehe Nachricht)
Thu27.10.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu03.11.202217:00 - 19:00Seminarraum BA 02C Vortragseinheitenentfällt auf Grund von Abwesenheit
Thu10.11.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu17.11.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu24.11.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu01.12.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu15.12.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu22.12.202217:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu12.01.202317:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu19.01.202317:00 - 19:00Seminarraum BA 02C Vortragseinheiten
Thu26.01.202317:00 - 19:00Seminarraum BA 02C Vortragseinheiten

Examination modalities

  • oral examination
  • Appointment after personal agreement


Course registration

Begin End Deregistration end
30.08.2022 12:00 22.12.2022 12:00


Study CodeObligationSemesterPrecon.Info
066 453 Biomedical Engineering Not specified
066 490 Technical Chemistry Mandatory elective


Registration is necessary to get access to documents

Previous knowledge

Basics of mass spectrometry from the lecture Analytical Chemistry 3 and the seminar structure elucidation are very beneficial.


if required in English