After successful completion of the course, students are able to apply concepts of metal catalysis, can identify important organometallic transformations (e.g. cross-coupling, C-H activation, etc.) and have an understanding of how to elucidate a reaction mechanism.
In the area of biocatalysis, students know important enzyme classes, the transformations they enable, and reaction parameters which are of specific importance in biocatalytic reactions.
In the area of organocatalysis, students know important classes of organocatalysts and the transformations they enable. They can also follow the principles of rational organocatalyst design.
Metallassistierte Synthesen (Advanced application of cross-coupling reactions; Orthogonal coupling methods; Coupling towards C-heteroatom bonds; Liebeskind-Srogl coupling; Tsuji-Trost reaction; Cyclopropanation; C-H activation; Cross-Dehydrogenative couplings; Oxidative coupling; Pd-Catalyzed Nucleophilic Substitution Reactions; Pd-catalyzed carbonylation; Aminopalladation; Rh-catalysis; Au-catalysis; Catalysis by non-precious metals)
Biocatalysis
Organocatalysis
Presentations of topics with time for questions.
Since this lecture is one of a series of lectures in the general subject of advanced organic chemistry, it is suggested to visit the lectures in this order: 1. OMC - 2. Strategies/Methods in Syntehsis - 3. Totalsynthese
Written exam, 10 questions, 10 points each.
Not necessary