After successful completion of the course, students are able to assess and predict phycial properties or organic compounds, select suitable analytical methods for compound characterization, apply rules of nomenclature to organic molecules, assess core properties of the discussed functional groups, decribe organic reactions based on the the corresponding reaction mechanisms, and define functional group interconversions including the required reagents and conditions.
Carbon, the key atom of organic compounds: electron configuration - hybridisation - ¿- and ¿-bonds - influence of electronic effects and the polarity of chemical bonds - reactive intermediates - electrophiles and nucelophiles - organic acids and bases - stereo structures of organic molecules - functional groups and the carbon backbone - basic principles of the nomenclature of organic molecules - mechanisms and reaction types: addition, substitution, elimination, condensation, reduction, oxidation, rearrangement, cycloaddition. Foundation of stereo chemistry: E/Z, cis/trans, racemate, inversion, retention; CIP rules; terms like chair, boat, antiperiplanar, synclinal etc. Correlation between structure, physicochemical properties and chemical reactivity of the most important classes of organic compounds such as: alkanes, alkenes, alkines, aromatic compounds, alkyl halides, metalorganic compounds (Grignard), alcohols, ethers, thioles, thioether, sulfoxides, sulfones, amines, N-oxides and their syntheses as well as their conversions; FGI (functional group interconversion) between the discussed classes of organic compounds.
Applying basic principles of organic reactions using the MO-concept as well as charge-distribution/polarization employing the concept of stabilizing elelctronic effects (inductive, resonance,...); description of representative reaction types emplying the concept of pushing electrons; suggesting additional examples via the control questions at the end of each chapter and encouraging additional examples from the accompanying work-book to the recommended text-book.
The lecture course starts March 4 in physical presence in the lecture hall.
Due to the current pandemic the format of the lecture can vary.
A recorded stream from a previous semester is accessible via TUWEL; slide material is available via TUWEL, as well - minor adjustments in various chapters may be conducted
ATTENTION: The lecture starts at 08:30 sharp every Monday - kindly make sure to be in the lecture hall in time!
NEW: After Easter a voluntary accompanying seminar OC1 163.193 will be offered - more details can be found directly in the TISS section of this course. Within this seminar class additional examples to topics of the lecture course will be discussed, moreover there will be the opportunity to repeat key content of the lecture together with reaction mechanisms and functional group transformations.
Currently, examinations will be carried on presence; however, depending on developments of the pandemic, this can change to an online format via ZOOM. For the online exam you need to have a PC or notebook available, which you use to display the exam questions, as well as a camera to transfer the video of you and your surroundings to the online meeting (e.g., external webcam, mobile phone or tablet).
The written exam includes the whole content of the lecture; it is based on understanding of concepts and the application on novel examples (which are derived from examples discussed within the lecture); fact-based knowledge will also be assessed in particular in context of functional group interconversions and analytical methods.
Exams last 120 minutes and consist of 10 questions from the following area:
English test editions can become available upon prior notification of the lecturer by email (min. 1 week before the test appointment)
Exams will be graded based on a maximum score of 100 points; grades are defined as: excellent/sehr gut 89-100 points, good/gut 76-88 points, average/befriedigend 63-75 points, sufficient/genügend 50-62 points, failed/nicht genügend below 50 points (requiring a follow-up exam)
In case of a close-call negative exam, an additional oral exam is offered (results from written and oral exams will be combined)
Not necessary
