After successful completion of the course, students are able to assess and predict phycial properties or organic compounds, select suitable analytical methods for compound characterization, apply rules of nomenclature to organic molecules, assess core properties of the discussed functional groups, decribe organic reactions based on the the corresponding reaction mechanisms, and define functional group interconversions including the required reagents and conditions.
Carbon, the key atom of organic compounds: electron configuration - hybridisation - ¿- and ¿-bonds - influence of electronic effects and the polarity of chemical bonds - reactive intermediates - electrophiles and nucelophiles - organic acids and bases - stereo structures of organic molecules - functional groups and the carbon backbone - basic principles of the nomenclature of organic molecules - mechanisms and reaction types: addition, substitution, elimination, condensation, reduction, oxidation, rearrangement, cycloaddition. Foundation of stereo chemistry: E/Z, cis/trans, racemate, inversion, retention; CIP rules; terms like chair, boat, antiperiplanar, synclinal etc. Correlation between structure, physicochemical properties and chemical reactivity of the most important classes of organic compounds such as: alkanes, alkenes, alkines, aromatic compounds, alkyl halides, metalorganic compounds (Grignard), alcohols, ethers, thioles, thioether, sulfoxides, sulfones, amines, N-oxides and their syntheses as well as their conversions; FGI (functional group interconversion) between the discussed classes of organic compounds.
Applying basic principles of organic reactions using the MO-concept as well as charge-distribution/polarization employing the concept of stabilizing elelctronic effects (inductive, resonance,...); description of representative reaction types emplying the concept of pushing electrons; suggesting additional examples via the control questions at the end of each chapter and encouraging additional examples from the accompanying work-book to the recommended text-book.
ATTENTION: The lecture starts at 08:30 every Monday - kindly make sure to be in the lecture hall in time!
NEW: After Easter a voluntary accompanying seminar OC1 163.193 will be offered Mondays 17:30-18:30 in lecture hall Knoller - more details can be found directly in the TISS section of this course. Within this seminar class additional examples to topics of the lecture course will be discussed, moreover there will be the opportunity to repeat key content of the lecture together with reaction mechanisms and functional group transformations.
The written exam includes the whole content of the lecture; it is based on understanding of concepts and the application on novel examples (which are derived from examples discussed within the lecture); fact-based knowledge will also be assessed in particular in context of functional group interconversions and analytical methods.
In case of a close-call negative exam, an additional oral exam is offered.