163.114 Medicinal Chemistry
This course is in all assigned curricula part of the STEOP.
This course is in at least 1 assigned curriculum part of the STEOP.

2022W, VO, 2.0h, 3.0EC
TUWEL

Properties

  • Semester hours: 2.0
  • Credits: 3.0
  • Type: VO Lecture
  • Format: Distance Learning

Learning outcomes

After successful completion of the course, students are able to apply general spects of pharmacodynamics and pharmacokinetics; they adopt an overview for the development of small-molecule drugs from the preclinical phase via clinical phases to market introduction. Students are familiarized with essential mode of action for small-molecule drugs and were introduced to general structure-activity relationships for core drug classes.

Subject of course

basics of drug activity (enzyme-drug interaction, pharmacodynamics, receptor concept, bioisosterism) drug mechanisms (enzyme inhibition and stimulation) development and structure optimization of drugs (SAR, COMFA, etc.) pro-drug/bio-precursor concept pharmacokinetics (ADME - absorption, distrubution, mebatolism, excretion) safety, toxicity, placebo effect regulatory aspects & intellectual property protection major classes of pharma drugs and agrochemicals incl. their corresponding mode of action

Teaching methods

Scientific approach employing hypothesis develoment and application within representative examples; reflecting particular problem situations emphasizing on mechanistic aspects.

Mode of examination

Oral

Additional information


Lecturers

Institute

Course dates

DayTimeDateLocationDescription
Mon11:00 - 13:0003.10.2022 - 23.01.2023Seminarraum BA 02A Medicinal Chemistry
Medicinal Chemistry - Single appointments
DayDateTimeLocationDescription
Mon03.10.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon10.10.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon17.10.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon24.10.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon31.10.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon07.11.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon14.11.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon21.11.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon28.11.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon05.12.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon12.12.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon19.12.202211:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon09.01.202311:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon16.01.202311:00 - 13:00Seminarraum BA 02A Medicinal Chemistry
Mon23.01.202311:00 - 13:00Seminarraum BA 02A Medicinal Chemistry

Examination modalities

Context based discussion of representative and novel examples derived from the lecture, in particular considering also the knowledge-based content of the lecture.

Course registration

Begin End Deregistration end
29.06.2022 00:01 30.11.2022 23:59

Curricula

Literature

Lecture notes for this course are available. Institutshomepage - Downloadbereich OC für Studenten Introduction to Medicinal Chemistry - Gringautz (VCH-Wiley) Medicinal Chemistry - King (RSC)

Language

German