This lecture offers a theoretical approach to modern total organic synthesis. The topics focus on the strategies to effect the generation of natural products by purely organic chemistry approaches. The course is a lecture and a seminar, where specific examples are discussed and relevant chemical approaches defined. Advanced organic synthesis is included.
Learning about the total synthesis of molecules, with a focus on stereoselective synthesis.
11.3. Sharpless-Epoxidierung + Hexosen (PG)
14.3. Dihydroxylierung + Zaragosic acid (PG)
21.3. Polyether + Brevetoxin (PG)
25.3. Aldol + Swinholide (VE)
1.4. Glycosylierung + Everninomicin (HM)
4.4. Makrocyclisierung (HM)
8.4. Atropisomerie + Vancomycin (VE)
11.4. Endiine + Dynemicin (VE)
29.4. Metathese + Epothilon (HM)
Not necessary