Biological meaning (of inorganic) of elements of the periodic table. Chemical, physical and thermodynamic relations: Speciation and their meaning (for example: H+, Zn2+, Fe2/3+), availability of the elements under anaerobic and aerobes conditions. Meaning of Lewis and Broensted acid and bases concepts in hydrophobic and hydrophilic environments: Complex formation and protonation-diprotonation reactions. Kinetic effects. Fe-integration, storage and transprot. Redox reactions: Redox active species, oxygen activation. The indivitual role elements: Alkali, alkaline earth metals, zinc, active centres in metal proteins: (Fe, Mn, Cu, Ni, CO, Mo, V, etc.) Bio-mineralization: biological crystallization and morphology. Medical aspects: Tracer items, cis platinum, Desferrioxamin. Hypotheses for the origin of the life (clay minerals, Fe-sulphides, cu hypothesis, etc.)