After successful completion of the course, students are able to summarise lipid synthesis, to explain the properties and processes in membrane biophysics, to discuss membrane transport and electric signalling as well as to analyse signalling via G-protein-coupled receptors.

Lipid Synthesis

• Classification
• Fatty Acid Synthesis
• Phospholipid Synthesis: Kennedy Pathways
• Ether Lipid synthesis
• Synthesis of Phosphatidylinositol
• Sphingolipid
• Synthesis
• Cholesterol Synthesis

Membrane Biophysics

• Pressure profile
• Bilayer thickness
• Phases in Lipid Bilayers: Gibbs phase rule
• Shape of lipids, curvature
• Connection to the cytoskeleton: spectrin, actin
• Lateral diffusion
• Asymmetry

Membrane Transport & Electric Signaling

• Permeability of Biomembranes
• Nernst potential, resting potential
• Ion channels
• Voltage-gated ion channels
• Action potential
• Chemical synapse

Signaling via G-protein-Coupled Receptors

Presentation and discussion of the subjects with the students.

Literature: Handouts will be offered

Mode: The lecture will be held via zoom every Wednesday 1500-1545. Meeting ID: 914 5744 9035; Password: 4Hc7a4Gf

Begin: The first lecture will be on March 3rd

oral exam on appointment. Estimated duration: 20 minutes